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[Remote] Engineering Manager, Native App & AI Platform

Work from home Full-time role Hiring

Note: The job is a remote job and is open to candidates in USA. Sequencing is a company focused on AI health experiences, and they are seeking an Engineering Manager for their Native App & AI Platform. This role involves leading a team to ensure delivery discipline, production reliability, and team health, while enhancing the mobile frontend and underlying AI platform.

Responsibilities

  • Own roadmap sequencing, delivery predictability, and capacity planning across the Native App and AI Platform
  • Drive predictable React Native releases across iOS and Android, with strong focus on frontend quality, product execution, and customer experience
  • Lead and develop a distributed team of engineers through coaching, regular 1:1s, hiring, performance management, and clear day to day accountability
  • Improve app performance, stability, and deployment reliability so customers can trust their health insights any time they open the app
  • Keep backend contracts and APIs clean and stable so mobile and platform teams can move quickly without creating friction or rework
  • Drive production grade implementation of multi agent architecture, planner agents, retrieval systems, model orchestration, and latency optimization
  • Build evaluation and regression checks into release workflows so health insights stay stable as the system evolves
  • Set and enforce clear targets for performance, reliability, and latency so the AI app responds in real time
  • Maintain clean architectural boundaries between AI platform and core systems so the platform remains understandable and maintainable over time
  • Build team resilience and reduce key person dependencies so the platform can scale sustainably
  • Lead AI related incident response, postmortems, and long term fixes so sensitive health data and insights stay dependable
  • Partner with Product, Bioinformatics, and Data to turn AI complexity into clear plans, accuracy guardrails, and measurable AI performance
  • Communicate clearly with leadership when focus is high on AI quality and reliability

Skills

  • 7+ years of engineering management experience working with high complexity, high visibility systems
  • Strong people management experience, including coaching, 1:1s, hiring, and performance management
  • Experience leading native mobile engineering teams, ideally with React Native across iOS and Android
  • Strong frontend and product delivery instincts, with ability to lead customer facing mobile experiences, not just backend execution
  • Experience leading AI infrastructure, AI platforms, or distributed backend teams handling sensitive or mission critical data
  • Familiarity with multi agent systems, planner agents, retrieval architecture, model orchestration, and ML backed production systems
  • Strong backend foundation in TypeScript or a similar production environment
  • Proven record of improving execution predictability and delivery discipline in engineering teams
  • Comfortable enforcing architectural guardrails and clean boundaries between systems and teams
  • Power user of AI and LLM tools for planning, communication, and process design. This is not optional
  • Strong command of project management and documentation tooling, including Jira, Confluence, and similar systems
  • Experience managing and supporting distributed teams in fully remote environments
  • Clear communicator who can turn deep technical details into simple operational plans for non technical partners

Company Overview

  • Sequencing is building the lifelong home for every genome on Earth and the foundational platform for the AI-native genomic era. It was founded in 2017, and is headquartered in Los Angeles, California, USA, with a workforce of 11-50 employees. Its website is https://sequencing.com.
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