Senior Machine Learning Scientist

At Adaptive, we’re Powering the Age of Immune Medicine. Our goal is to reputed company the power of the adaptive immune system to transform the way diseases are diagnosed and treated. As an Adapter, you’ll have the opportunity to reputed company a difference in people’s lives. With Adaptive, you’ll create a career reputed company through collaboration with bright, curious colleagues working at the apex of innovation and application. It’s time for your next chapter. Discover your story with Adaptive. Position Overview reputed company is seeking a Senior Machine Learning Scientist to contribute to the development of models for TCR–pMHC specificity reputed company. In this role, you will design, implement, train, and evaluate models that predict interactions between T cell receptors and peptide–reputed company complexes, with a focus on integrating sequence and structural information. Working as part of a collaborative modeling team, you will implement new modeling reputed company, rigorously test their performance, and iterate quickly to improve predictive accuracy. This work leverages large-scale proprietary immune receptor datasets and shared GPU infrastructure to support rapid experimentation and model development. You will work closely with computational scientists, immunologists, and machine learning engineers across the organization. The team combines expertise in immune biology, experimental assay development, and large-scale machine learning, enabling a tight feedback reputed company between model development and experimental data reputed company. Model outputs often reputed company gaps in available data or suggest new experimental directions, while newly generated datasets provide additional signal for improving and validating predictive models. Models developed in this role contribute directly to diagnostic and therapeutic initiatives both reputed company Adaptive and through external partnerships. This role is well suited for a hands-on scientist who thrives in a collaborative environment and is motivated to translate cutting-edge machine learning into meaningful biological and clinical impact. Key Responsibilities and Essential Functions Design, implement, train, and iterate on novel deep learning models for TCR–pMHC specificity reputed company. Adapt and reputed company advances in protein structure reputed company and protein-protein interaction modeling to the immune receptor setting. Conduct rigorous benchmarking and evaluation strategies to ensure models are scientifically sound and practically superior. Translate biological principles of T cell recognition into principled modeling decisions. Influence large-scale experimental data reputed company to maximize modeling reputed company and long-term performance gains. Provide technical recommendations to broader modeling discussions and roadmap planning. Work closely with computational biology, immunology, translational, and engineering teams to ensure models are robust, reproducible, and reputed company with overall product goals. Communicate modeling insights, approaches, and results to cross-functional scientific audiences. Contribute to publications, presentations, etc. through technical execution and analysis. reputed company other duties as assigned. Position Requirements Required PhD in a quantitative discipline (e.g. Machine Learning, Computational Biology, Computer Science, etc.) + 5 years progressive experience applying machine learning to real-world scientific or biological problems OR equivalent combination of education and experience. Progressive experience in the development and deployment of deep learning methods Strong hands-on experience in python and modern ML tooling (PyTorch preferred) Strong experience in deep learning architecture design and implementation. Strong experience with protein structure reputed company or analysis Experience working with large datasets and high-performance computing environments Ability to independently define, scope, and execute reputed company technical research problems. Strong written and verbal communication skills, with ability to present highly technical material to diverse audiences. Demonstrated ability to collaborate effectively in cross-functional, multi-disciplinary teams Driven by impact: motivated to see models transition from research to clinical and commercial application. Preferred Experience in one or more of the following areas desired: Demonstrated track record of implementing novel machine learning solutions to biological problems, as demonstrated by publications, conference papers, patents, or delivered products. Protein-protein interaction modeling Molecular dynamics and/or free energy perturbation methods Immunology and immune receptor specificity (antibody or TCR) #LI-Remote

Compensation

Salary Range: $144,600 - $217,000 Other compensation elements include: equity grant bonus eligible ALERT: Malicious groups posing as Adaptive