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[Remote] Software Engineer III, Voice AI

Work from home Full-time role Hiring

Note: The job is a remote job and is open to candidates in USA. Natera is a global leader in cell-free DNA testing, dedicated to oncology, women’s health, and organ health. They are seeking a Software Engineer III to design, develop, and maintain their Voice AI platform, which enhances patient access to genetic testing results through automated call handling.

Responsibilities

  • Take ownership of assigned voice AI features and components, guiding them through the full software development lifecycle
  • Contribute to design discussions, code reviews, and best practice adoption within the Voice AI team
  • Drive technical decisions on voice pipeline optimization — VAD tuning, turn-taking, interruption handling, and latency management
  • Plan and prioritize tasks in an Agile environment, ensuring timely and high-quality delivery
  • Work with Product Managers and stakeholders to refine requirements and scope technical efforts for conversational AI features
  • Monitor voice platform health metrics (call efficacy, ASR accuracy, per-segment latency) and prioritize improvements based on data
  • Mentor junior team members, sharing knowledge and best practices in voice AI architecture, TypeScript, and real-time systems
  • Encourage a culture of continuous learning and technical excellence through pair programming and design reviews
  • Document voice AI patterns, integration contracts, and operational runbooks for the team
  • Partner with Product Managers, QA, and clinical operations to gather requirements, validate conversational designs, and guide projects from inception to deployment
  • Coordinate with other engineering teams to integrate voice agents with internal services via authenticated APIs
  • Work with the analytics team to ensure voice metrics flow correctly through the data pipeline for reporting and optimization
  • Drive improvements in our multi-agent orchestration approach — tool calling patterns, agent handoff logic, and state management across conversation turns
  • Advocate for high-quality standards and automated testing strategies for conversational AI systems, including voice-specific test patterns (simulated calls, transcript validation, latency benchmarks)
  • Identify and resolve voice-specific UX issues: ASR errors on medical terminology, silence detection tuning, barge-in recovery, and end-to-end response latency

Skills

  • 5+ years of overall software development experience, focusing on scalable backend services using Node.js and TypeScript
  • 1+ years of experience with voice AI, conversational AI, or real-time audio systems in production
  • Hands-on experience with agentic LLM architectures — tool calling, multi-agent orchestration, prompt engineering, and conversation state management
  • Familiarity with voice AI pipeline components: STT (Deepgram, Azure Speech, OpenAI Whisper), TTS (ElevenLabs, OpenAI, Cartesia), and LLM APIs (OpenAI Realtime API, Anthropic Claude)
  • Experience with telephony systems — Twilio (media streams, SIP, IVR) or equivalent WebSocket-based audio streaming platforms
  • Understanding of voice-specific challenges: VAD configuration, turn-taking, interruption handling, latency budgets, and audio codec management (mulaw/PCM)
  • Solid understanding of the software development lifecycle (SDLC), including build, configuration, release, and deployment
  • Knowledge of microservice architecture and distributed systems best practices
  • Proficiency with AWS services (ECS Fargate, Lambda, DynamoDB, S3, Kafka/MSK, API Gateway)
  • Experience with event-driven architecture and message processing (e.g., Apache Kafka, SQS)
  • Strong relational database skills (MySQL) and exposure to NoSQL databases (DynamoDB, Redis)
  • Demonstrated teamwork skills and a collaborative mindset
  • Excellent communication and organizational skills
  • Experience with RAG architectures (AWS Bedrock, vector stores, embedding models)

Benefits

  • Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents
  • Free testing for Natera employees and their immediate families
  • Fertility care benefits
  • Pregnancy and baby bonding leave
  • 401k benefits
  • Commuter benefits
  • Generous employee referral program

Company Overview

  • Natera specializes in cell-free DNA testing to provide a more targeted interventions to oncology, women's health, and organ health. It was founded in 2004, and is headquartered in San Carlos, California, USA, with a workforce of 5001-10000 employees. Its website is https://www.natera.com/.
  • Company H1B Sponsorship

  • Natera has a track record of offering H1B sponsorships, with 13 in 2026, 90 in 2025, 72 in 2024, 37 in 2023, 71 in 2022, 64 in 2021, 40 in 2020. Please note that this does not guarantee sponsorship for this specific role.
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