Observational Research Manager (Pharmacovigilance Epidemiology and Causal Inference / Obesity)

Career Category Clinical Job Description Level 5 Requisition for Observational Research, Manager (Pharmacovigilance Epidemiology and Causal Inference / Obesity) Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Observational Research, Manager (Pharmacovigilance Epidemiology and Causal Inference / Obesity) What you will do Let’s do this. Let’s change the world. Do you want an exciting position working with the obesity therapeutic area and pharmacovigilance epidemiology/causal inference teams to generate real world evidence supporting a wide variety of business needs? Observational research (OR) is an increasingly important component in drug development and commercialization, because in the current environment, there is increased demand for information from OR studies for regulatory and reimbursement authorities. The Center for Observational Research (CfOR) at Amgen partners with teams to generate real world evidence for multiple stakeholders across the product lifecycle. CfOR studies include but are not limited to evidence generation regarding the frequency and distribution of disease, the clinical burden of disease, the natural history or clinical course of disease, the design of clinical trials, treatment cost and utilization patterns, and the safety and effectiveness of therapeutic interventions. ​ Amgen is searching for an Observational Research Manager (Epidemiology). This manager will have responsibilities for research activities supporting the obesity pipeline products and will report directly to the lead for the Pharmacovigilance Epidemiology and Causal Inference team in the Data and Analytics Center (DAC). A CfOR manager is recognized as a strong scientific contributor and is a first or contributing author for papers in peer-reviewed journals, abstracts for scientific congresses or for internal reports that enhance the company’s mission. This position may be located at Amgen's Thousand Oaks headquarters or be remote. Key Activities include: Design and execute studies based on causal inference frameworks to support evidence generation such as identifying appropriate patient populations, assessing disease burden and resource utilization, obtaining product registrations and label-expansions, meeting post-marketing requirements/commitments, and product differentiation Identify opportunities to substitute for and/or complement interventional studies to reduce time and cost of drug development Influence cross-functional stakeholders as to the appropriate use and timing of non-interventional research to answer high-priority strategic business questions Leverage real-world data and CfOR analytic approaches to inform high-value business decisions for multiple stakeholders Contribute to the mission of CfOR, including progressing innovative epidemiological methods and analytical capabilities to support CfOR’s leadership role within Amgen and industry What we expect of you Basic Qualifications: Doctorate degree OR Master's degree and 3 years of scientific experience OR Bachelor's Degree and 5 years of scientific experience OR Associate’s degree and 10 years of scientific experience OR High school diploma / GED & 12 years of scientific experience Preferred Qualifications: Doctorate in Epidemiology or other subject with high observational research content Experience in the design, execution, and analysis of observational research studies within Pharmaceutical or Public Health setting Experience in applying causal inference frameworks such as target trial emulation or the causal roadmap to generate real-world evidence Experience in research to support drug development Experience working with secondary data systems, including administrative claims, EMR, registries Experience in observational research project planning and management Excellent verbal and writing communication and interpersonal skills Experience working in multi-disciplinary teams What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our c