[Hiring] Bioinformatics Pipeline Validation Manager @OMG Technology

Role Description We are seeking an experienced Bioinformatics Pipeline Validation Manager to lead validation efforts for bioinformatics pipelines. This individual will manage a team responsible for ensuring that computational pipelines used in genomics and clinical research meet regulatory, quality, and performance standards. This role is within a life sciences organization focused on advancing molecular diagnostics and genomic technologies. The ideal candidate will bring strong bioinformatics, NGS pipeline validation, cancer genomics experience, and leadership experience, along with a deep understanding of regulated environments such as GxP, CLIA, or CAP.

Key Responsibilities

• Leadership & Team Management
• Lead, mentor, and develop a team of bioinformatics validation scientists and analysts.
• Oversee workload planning, project assignments, and team performance tracking.
• Foster a collaborative, high-performing team culture focused on quality, efficiency, and innovation.
• Pipeline Validation & Quality Assurance
• Own end-to-end validation of bioinformatics pipelines, including NGS, WGS/WES, RNA-seq, variant calling, annotation, and QC workflows.
• Develop and execute validation plans, protocols, test cases, and acceptance criteria.
• Ensure pipelines meet applicable regulatory requirements (e.g., CLIA, CAP, FDA).
• Perform software verification and validation (SV&V) and document results thoroughly.
• Technical Expertise & Execution
• Collaborate with bioinformatics engineers, data scientists, and software developers to optimize pipeline design and performance.
• Evaluate new tools, algorithms, and software for integration into analytical workflows.
• Troubleshoot pipeline issues and lead root-cause analysis efforts.
• Ensure reproducibility, scalability, and robustness of computational workflows.
• Cross-Functional Collaboration
• Partner with wet lab teams, QA, clinical operations, and product management to align validation objectives with timelines and business goals.
• Represent the validation team in client meetings, audits, and technical reviews.
• Documentation & Compliance
• Maintain detailed documentation of validation activities, including version control and release notes.
• Prepare documentation for regulatory submissions and internal audits.
• Establish and enforce validation standards, SOPs, and best practices.

Qualifications

• 10+ years of experience in bioinformatics, genomics data analysis, cancer genomics pipeline validation.
• 4+ years of leadership or management experience leading technical teams.
• Strong experience with NGS data processing pipelines, including quality control, alignment, variant calling, annotation, and interpretation.
• Hands-on experience with bioinformatics workflow management tools such as Nextflow, Snakemake, WDL, Cromwell, or Galaxy.
• Experience with common NGS analysis tools such as BWA, Bowtie2, GATK, SAMtools, Picard, FastQC, MultiQC, and VEP/ANNOVAR.
• Experience with containerization and reproducibility tools such as Docker, Singularity/Apptainer, and workflow environment management tools like Conda or Bioconda.
• Proficiency in scripting or programming languages such as Python, R, or Bash.
• Experience working in regulated environments (GxP, CLIA, CAP, or similar).
• Familiarity with software validation lifecycle, automated testing, and documentation practices.
• Bachelor’s or master’s degree in bioinformatics, Computational Biology, Genomics, Computer Science, or related field.

Preferred Qualifications

• Experience supporting clinical genomics or diagnostic pipelines.
• Knowledge of cloud platforms such as AWS, Google Cloud Platform, or Azure used for scalable bioinformatics workflows.
• Experience with CI/CD tools such as Jenkins, GitLab CI, or GitHub Actions.
• Experience managing large-scale genomic datasets and distributed computing environments.

Other Job Details

• Location: Remote
• Candidate rate: $65 on C2C and $60 on W2
• Docs required: ID proof will be required.
• Location: New Jersey, New Jersey (Remote)
• Employment Type: Contractor
• Minimum Experience: Manager/Supervisor